Coronavirus has mutated to a far more aggressive strain – Scientists

Coronavirus has mutated into two strains, one which appears to be far more aggressive, scientists have said, in a discovery which could hinder attempts to develop a vaccine.

The older ‘S-type’ appears to be milder and less infectious, while the ‘L-type’ which emerged later, spreads quickly and currently accounts for around 70 per cent of cases.

The Telegraph reports that researchers at Peking University’s School of Life Sciences and the Institut Pasteur of Shanghai, discovered the virus has evolved into two major lineages – dubbed ‘L’ and ‘S’ types.

The research report says whereas the L type was more prevalent in the early stages of the outbreak in Wuhan, the frequency of the L type decreased after early January 2020. Human intervention may have placed more severe selective pressure on the L type, which might be more aggressive and spread more quickly.

On the other hand, the S type, which is evolutionarily older and less aggressive, might have increased in relative frequency due to relatively weaker selective pressure. These findings strongly support an urgent need for further immediate, comprehensive studies that combine genomic data, epidemiological data, and chart records of the clinical symptoms of patients with coronavirus disease 2019 (COVID-19)

Telegraph / Oxford National Science Review

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